MitoLink
Launch Galaxy| Public Server: | MitoLink Server (IN) |
|---|---|
| Virtual Machine: | MitoLink Virtual Machine |
| Scope: | Domain Specific |
| Summary: | [MitoLink](https://datascience.imtech.res.in/anshu/mitolink) is an integrated workflow system to facilitate understanding of genotype-phenotype correlations in cases of mitochondrial dysfunction. |
Comments
- Provides a complete pipeline based system to analyse and visualize the role of SNPs in Mitochondrial Diseases.
- It also provides an in-house mitochondrial protein repository which allows to elucidate the role of the both mitochondrial and nuclear genome in mitochondrial dysfunction.
- Integrated data from the GenomeAsia Pilot Project, gnomAD, DisGenNET and ClinVar to understand impact of genomic variation through gene-disease networks.
User Support
- [MitoLink User Manual](https://ab-openlab.csir.res.in/mitolink_v1/static/mitolink/User_Manual.pdf)
- [Shared Data Library](https://ab-openlab.csir.res.in/mitolink_v1/library/list)
- [Workflows](https://ab-openlab.csir.res.in/mitolink_v1/workflows/list_published)
Quotas
- Anyone can create an account. MitoLink can also be accessed anonymously.
- There are no quotas on the VM version.
Citations
- Kumar, R., K Rajput, N., Jolly, B., Narwade, A., & Bhardwaj, A. (2021). [MitoLink: A Generic Integrated Web-based Workflow System to Evaluate Genotype-Phenotype Correlations in Human Mitochondrial Diseases: Observations from The GenomeAsia Pilot Project](https://doi.org/10.1016/j.mito.2021.09.005). *Mitochondrion*. https://doi.org/10.1016/j.mito.2021.09.005
- MitoLink tagged publications in the Galaxy Publication Library
Sponsors
- Early Career Research Award - SERB and CSIR-Institute of Microbial Technology
- [CSIR-Institute of Microbial Technology](https://www.imtech.res.in/facilities/bioinformatics-centre-bic), [Academy of Scientific and Innovative Research (AcSIR)](https://acsir.res.in/), [CSIR Institute of Genomics and Integrative Biology (CSIR-IGIB)](https://www.igib.res.in/), [CSIR-Open Source Drug Discovery Consortium](http://www.osdd.net/)